Evidence of meeting #108 for Veterans Affairs in the 42nd Parliament, 1st Session. (The original version is on Parliament’s site, as are the minutes.) The winning word was cannabis.

A recording is available from Parliament.

On the agenda

MPs speaking

Also speaking

Karen Ludwig  New Brunswick Southwest, Lib.
Shaun Chen  Scarborough North, Lib.
James MacKillop  Peter Boris Chair in Addictions Research, St. Joseph's Healthcare Hamilton, McMaster University, As an Individual
Kyle Atkinson  As an Individual
Andrew Freedman  Director, Freedman and Koski Inc.

4 p.m.

Liberal

The Chair Liberal Neil Ellis

We don't have unanimous consent.

Do you want to take those as notices of motions for the next meeting?

4 p.m.

Conservative

Phil McColeman Conservative Brantford—Brant, ON

I absolutely do.

I'd like to be able to speak to the fact that we are missing the opportunity here to scrutinize the money spent—some $323 million, as written in supplementary estimates (B)—for Veterans Affairs Canada. That's $323 million that this committee will not be scrutinizing.

4 p.m.

Liberal

The Chair Liberal Neil Ellis

Today we're on medical cannabis. Let's start—

Yes, Cathay.

4 p.m.

Conservative

Cathay Wagantall Conservative Yorkton—Melville, SK

On a point of order, just very briefly, when we discussed the schedule to up until the end of June, there was time set aside and an agreement that we would have the Minister of Veterans Affairs come and speak to—

4 p.m.

Liberal

Darrell Samson Liberal Sackville—Preston—Chezzetcook, NS

March 20 is what was in our calendar.

4 p.m.

Conservative

Cathay Wagantall Conservative Yorkton—Melville, SK

—the supplementary estimates. The deadline for that to happen is next week. To me it's counterintuitive that you would not simply agree to have the interim minister come on February 25 or February 27, before the time for this committee to do its work, to challenge the estimates, is to take place.

4 p.m.

Liberal

The Chair Liberal Neil Ellis

I'm sorry, but you're debating again. We're on medical cannabis today, and I'd like to get the meeting started.

Yes, Mr. Kitchen.

4 p.m.

Conservative

Robert Gordon Kitchen Conservative Souris—Moose Mountain, SK

On a point of clarification, correct me here, or please explain to me how.... We have to talk about the estimates by the end of next week. We have a minister who's set to come supposedly in March. He's going to come and talk about the estimates, which will already have been done. How is that—

4 p.m.

Liberal

Doug Eyolfson Liberal Charleswood—St. James—Assiniboia—Headingley, MB

On a point of order, we have a meeting agenda. We have witnesses who are going to give testimony, and that's on the agenda. What is being talked about right now is committee business. This should be under committee business.

We should be starting the meeting, as per the agenda, unless we have unanimous consent from the committee, and I don't believe we have that.

4 p.m.

Liberal

The Chair Liberal Neil Ellis

We'll start the meeting.

4 p.m.

Conservative

Robert Gordon Kitchen Conservative Souris—Moose Mountain, SK

Can I not get a clarification?

4 p.m.

Liberal

The Chair Liberal Neil Ellis

You can make a point of order.

4 p.m.

Conservative

Robert Gordon Kitchen Conservative Souris—Moose Mountain, SK

My point of order is that I need clarification. We have dates that don't coincide with the forms that we have.

4 p.m.

Liberal

The Chair Liberal Neil Ellis

The point of order was unanimous consent. We didn't receive unanimous consent, so we're not debating it.

We'll start with our first witness.

Mr. MacKillop, you have 10 minutes.

February 20th, 2019 / 4 p.m.

Dr. James MacKillop Peter Boris Chair in Addictions Research, St. Joseph's Healthcare Hamilton, McMaster University, As an Individual

Good afternoon, honourable members of Parliament. I appreciate the opportunity to address this committee on this important topic.

At McMaster University and St. Joseph's Healthcare Hamilton, I hold the Peter Boris chair in addictions research, and I direct the Peter Boris Centre for Addictions Research and the Michael G. DeGroote Centre for Medicinal Cannabis Research.

I've dedicated my career to understanding addiction and, more recently, to advancing the science of medical cannabis.

With regard to the DeGroote Centre, I want to note that the central operations of the centre are supported by philanthropy, not by industry. Our mission is to develop an evidence-based understanding of medical cannabis both in terms of positive therapeutic effects and potential negative side effects.

Our highest priority is the objective study of cannabis, just like any other drug in medicine.

We exist not because we believe that cannabis is or is not an effective medicine, but because we're sure there's a need for more research on the topic.

I've personally published research documenting both the risks and harms from cannabis use and also its potential therapeutic applications. I'm neither pro-cannabis nor anti-cannabis. I am pro-evidence, and I'm pro evidence-based medicine and pro evidence-based policy.

As a preface to my comments, I am mindful of the sacrifices that are made by veterans. As part of my clinical training, I was at the U.S. Providence veterans administration hospital working directly with veterans. I'm aware of how common the conditions they often use cannabis for are and that those conditions are often a result of their service.

Moreover, over 8,000 Canadian veterans are currently authorized for medical cannabis, and I know that the decisions around policies will have significant effects on their lives.

My comments today are from the perspective of trying to use the best available evidence to advance the health and well-being of Canadian veterans.

I'm aware of the six priority topics, and I will comment on three areas where I have the greatest expertise. I'm happy to discuss other topics also.

The first priority topic is the scientific basis for the policy for reimbursement of up to three grams of cannabis in general and up to 10 grams with additional approval, and that's daily.

Is this amount the right amount? Is it too high? Is it too low? Unfortunately, precise dosing is not available from the current research. This is one of the ways that medical cannabis is different from traditional medicine.

The reality is that this is not a drug with a DIN, a drug identification number, like other drugs have. It's a plant, not a pill. It's a plant that has dozens of different compounds that interact with the body's internal endogenous cannabinoid system. The interaction of these compounds is believed to be part of the reason for its positive effects.

In addition, there are many different routes of administration, not just as a capsule, like most medications, but via inhalation and other routes. This could affect the effects, also.

To put this in context, for non-medical users three grams daily would be considered a very high level of use, and 10 grams daily would be considered an extremely high level of use. In research, we standardize a gram as being equivalent to about four cannabis cigarettes, or joints. These numbers equate to 12 and 40 joints per day, which would be a large amount of cannabis.

The reality is that pharmacology doesn't make any distinction between medical use and non-medical use. The more cannabis a person consumes, the higher the risk of adverse consequences.

A person who's consuming, for example, 10 grams of cannabis each day would be more likely to experience physiological dependence and other adverse side effects, such as cognitive difficulties, motor impairment, or risk for cannabis-use disorder, the technical term for addiction to cannabis. It's also the case that withdrawal symptoms would be more likely in high-dose patients.

In this context, I am not proposing or recommending any immediate changes or restrictions. The reality is that abruptly reducing access or making other policy changes that would dramatically increase the cost of cannabis to active medical patients could have adverse consequences.

I do believe, however, it's important that veterans who are using medical cannabis do so closely in contact with their treatment providers to monitor their progress and minimize potential harms.

With regard to the second topic, evidence for medical cannabis for chronic pain and PTSD, unfortunately, the utilization of cannabis in these contexts has outpaced the research on this topic.

For chronic pain, a recent review of numerous studies suggested that there is a small therapeutic effect on pain, but there were high rates of side effects, and the side effects were more common than the positive response.

In another recent review, when restricted to neuropathic pain, there was again evidence of a positive effect, this time larger than for general pain, but side effect rates were very high and patients who were taking medical cannabis for pain were more likely to drop out of trials.

On balance, both of these reviews concluded that although there is positive evidence for pain, the evidence for side effects may suggest that the benefits are outweighed by the harms. It's also worth noting that in these reviews, no trials to date have been conducted on Canadian veterans, so all of this is by analogy, rather than based on evidence we have in this population.

With regard to PTSD and other anxiety disorders, there are intriguing preclinical findings using animal models. There are anecdotal and case study reports that are promising, but there are no gold standard randomized controlled trials that show evidence of efficacy, either in civilian or veteran populations. At this point, there is insufficient evidence that cannabis is effective in treating PTSD or other anxiety disorders.

These are my personal conclusions, but they are very similar to the conclusions reached in a recent report by the U.S. Department of Veterans Affairs with regard to the benefits and harms of cannabis for pain and PTSD for United States veterans.

There are other circumstances in which cannabis has been shown to be helpful: reducing chemotherapy-induced nausea and vomiting, reducing spasticity in multiple sclerosis and reducing seizure frequency in children with rare pediatric seizure disorders. These are all areas where the evidence is more robust. That is not the case for pain and PTSD.

On the topic of how legalization will affect medical cannabis for veterans, there's a risk that individuals who have current authorizations may augment the amount available with additional non-medical cannabis that is legal. It's also possible that veterans who are considering getting an authorization will simply explore it and self-medicate without engaging with a health care provider. This could result in harms by way of individuals inadvertently accessing products that would be considered high risk. High THC products that have low rates of CBD can have a cannabidiol, a constituent that's believed to be responsible for the therapeutic actions to an extent.

The other reality is that, because there are known risks, any medical use, in my opinion, should take place in collaboration with a health care provider.

Finally, given that the market for recreational cannabis will necessarily be much larger than the medical cannabis market, it's possible that the products used primarily for medical purposes will become increasingly unavailable. Those are products like oral capsules, oral oils or high CBD products. In my opinion, it's important that Health Canada's dual system for medical and recreational cannabis be fully implemented and supported.

In this context, I would argue that there's a high need for large scale, coordinated research on medical cannabis for veterans in Canada. There are literally thousands of veterans who are effectively accessing what could most charitably be described as an experimental medicine, rather than an evidence-based medicine. Because there is evidence from U.S. veteran populations of the association of cannabis with suicidality and self-harm, the risk for true harm is present.

In terms of the research that we need, we need observational research to understand the effects that are happening among individuals who are currently using cannabis. We also need randomized control trials to actually test, using gold standards, cannabis for pain and PTSD. We also need more knowledge translation and guideline development efforts to make veterans aware of the realities of risks, and to give clinicians clear recommendations about best practices.

As a final point, it's important to remember that Canada still has a major opioid epidemic that has not abated. Increases in access to opioids, and a combination of overestimated efficacy and underestimated risk has contributed to the current epidemic. Those are lessons to be learned in the context of medical cannabis and for cannabis post-legalization in general. In my opinion, the bottom line is that excessive optimism can lead to real harm here.

Thank you for the opportunity to serve as a witness for this committee.

4:10 p.m.

Liberal

The Chair Liberal Neil Ellis

Thank you.

Mr. Atkinson, the floor is yours for 10 minutes.

4:10 p.m.

Kyle Atkinson As an Individual

Thank you.

Good afternoon. Thank you for the opportunity to speak with you today. It's my pleasure to highlight my experience in helping veterans in a medical and professional setting as it relates to cannabis.

First, it is important for you to know that I am not a veteran of the Canadian Armed Forces or a member of a first responder organization. I am not a health care professional. I am an entrepreneur with a pharmaceutical and start-up technology background who realized that there was a serious issue with the way Canadians were accessing medical cannabis, and I wanted to do something about it.

I saw an opportunity to change the narrative around medical cannabis and also fill in some of the gaps that exist for soldiers exiting the military. I started an organization called Trauma Healing Centers over four years ago, which is not to be confused with an organization called Marijuana for Trauma.

In the 3.5 years under my leadership, we have helped 7,500 patients. Approximately 900 of them were veterans of the Canadian Armed Forces. Approximately 90% of the 7,500 patients who were referred to Trauma Healing Centers had already tried cannabis, and it happened to work for their condition or conditions. They didn't know how it worked or why it worked, but it provided the symptom relief that they desperately needed and the therapy significantly increased their quality of life.

Trauma Health Centers' approach is via multidisciplinary care. I have physicians, nurses, psychologists, social workers, dietitians, massage therapists and peer-support advisers all under one roof to help our patients. Patients have come to us via other physicians, either a GP or specialist referral.

For those who are not aware, medical cannabis is a last-resort treatment option. When all indicated medications and therapies have been exhausted, medical cannabis can be tried. As physicians would say, this is where the art of medicine comes into play.

Medical cannabis is not a silver bullet. It must be managed in a medical and professional way to ensure that positive outcomes are achieved. When positive outcomes are not achieved, physicians must discontinue the patient's cannabis authorization like they would any other medication. The vast majority of our patients were able to reduce or discontinue their existing pharmaceutical regimen when cannabis was helping to improve their symptoms.

I will be the first to say that there is no strong evidence for medical cannabis use in any medical condition, and that large-scale randomized clinical trials need to be conducted to ensure maximum benefit can be achieved with minimal risk. However, the lack of evidence is not proof of the lack of benefit. The key is managing the treatment in a medical and professional way in order to maximize the potential benefits and minimize the potential risks.

Unfortunately, there are many physicians in Canada who are authorizing medical cannabis in a risky manner. They are often not adhering to a start-low, go-slow approach. Some are authorizing medical cannabis with little or no knowledge of how cannabis works and are leaving patients to self-treat, which is really no different from patients buying off the street. Helping patients become—quote—“legal” is not the objective; helping them achieve symptom relief and improve quality of life should be the objective.

I am fortunate to have had many amazing physicians work for me over 3.5 years at Trauma Healing Centers. Most were GPs with experience in pain management and addictions. Some had occupational health experience and worked with their provincial workers compensation boards. Two were specialists—psychiatry and pain management—and two were veterans of the Canadian Armed Forces.

We were able to gain trust and to partner with many organizations that are tremendous advocates for the well-being of veterans. Wounded Warriors Canada, VETS Canada, MFRC, and the Royal Canadian Legion are just a few that have come to understand and believe in our approach.

I was also able to gain the trust of the director of policy for Veterans Affairs who was responsible for the medical cannabis file. My medical director and I supported the capped reimbursement to three grams per day, the need for special authorization beyond three grams per day and the inclusion of oil reimbursement.

I have spoken to hundreds of veterans and their families who have explained how cannabis has greatly improved their medical condition or conditions, and enhanced their quality of life. I have met with many of the highest-ranking officials in the military who care about the well-being of their members and former members.

I met with Surgeon General Downes at the 2017 CIMVHR conference and explained our approach and the results we were seeing. My team and I met with General Vance, with the intention of making him aware of what we are doing to ensure that his veterans suffering from chronic conditions, like PTSD and pain, are getting help via a multidisciplinary care approach.

We also made three simple recommendations that we felt could have a profound impact on the outcomes for veterans who struggle with medical conditions leaving the military.

We recommended that Canadian Armed Forces members who were exiting the military with pensionable conditions should access multidisciplinary care off base prior to being discharged so that they may continue with their care regimen uninterrupted and not have to wait for benefits to kick in via Veterans Affairs Canada to access care.

We recommended that all military members discharged with pensionable conditions be assigned a peer support adviser several months prior to their discharge date to ensure they had the support of someone on their level who had been through the process and could help guide them.

We recommended that the Operation Family Doc pilot program in Ottawa be expanded to other parts of the country to ensure that medically discharging members have a continuity of primary case services.

In closing, I strongly feel that much more can be done to improve the outcomes of veterans utilizing a multidisciplinary care approach and coordinated care. I also strongly believe that medical cannabis can be utilized as part of this approach.

Thank you for your attention.

4:20 p.m.

Liberal

The Chair Liberal Neil Ellis

Thank you.

Mr. Freedman.

4:20 p.m.

Andrew Freedman Director, Freedman and Koski Inc.

Thank you, Mr. Chair, for having me appear before the committee.

For those who don't know, I was the director of marijuana coordination under Governor Hickenlooper in Colorado for the rollout of what we referred to as medical and recreational marijuana. I have since started a firm that works primarily directly for government and also ancillary businesses; however, we do not take money from the marijuana industry or cannabis industry as that would be in tension with...a conflict with our other work.

I'm obviously not a public health expert nor a veteran, and what I hope to speak to you about today—and maybe it's most appropriate that I'm coming last—is really the unfortunate policy tension that has arisen as a result of federal and really worldwide prohibition on cannabis research.

What you're dealing with is one of the more sympathetic communities, along with children with intractable epilepsy, who have really suffered from the lack of efficacy research at the top levels of government for what cannabis can do for PTSD.

That lack of research over a period of time, with anecdotal evidence that this was being helpful, has turned this policy debate from what would normally be for any other substance a guilty-until-proven-innocent model into an innocent-until-proven-guilty model of dealing with the substance in such a way that we are going to assume benefits under anecdotes and smaller research faster than we would for a different substance.

I'm not suggesting that is the wrong approach to take here. I'm simply stating that is what has happened because of this worldwide prohibition on the sort of research that would be needed here.

That community is clearly tired of waiting for traditional institutions to catch up, and over time, there has been more and more of a push for right to access and use, hopefully with financial reimbursement and with physician oversight.

However, research is direly needed in this space, in my opinion, most clearly for drug-to-drug interactions, especially for people who might be in a PTSD situation and already are on a certain drug. Research is also needed on side effects, such as liver toxicity, and on specific formulations for drug efficacy: What is working? Why is it working? How can we research that?

The tension that is arising here is that, while some of this may be done with public research money, in particular in Canada more than in the United States, you can make great strides forward with public research and rigorous work through people like Dr. MacKillop. There will be a need to continue to have a path towards profitability for companies, for pharmaceutical companies, to continue to incentivize research in this area and continue to really put in what is going to be more billions of dollars—rather than even hundreds of millions of dollars—to prove that it is safe but also to find the most efficacious formulas.

The mission that I believe is in front of this committee today is to figure out a way to provide access to these communities that have been waiting for long periods of time to have access to it while continuing to provide incentives for research moving forward and really thinking about the long-term research prospects for providing effective safe medicines to these communities.

I think this will be a particularly difficult goal considering adult use legalization is coming online as well. As mentioned before, that will lead to self-medication in the marketplace. Nevertheless, I do think that you will have to consider the path forward of how you provide access, and how you provide continuing incentives to research in this area.

With that, I'd be happy to answer any questions.

4:25 p.m.

Liberal

The Chair Liberal Neil Ellis

Thank you.

We will begin our first round of questions with Mr. McColeman.

4:25 p.m.

Conservative

Phil McColeman Conservative Brantford—Brant, ON

Thank you, Chair.

Mr. Freedman, you said that you were part of the rollout in Colorado. Is that correct?

4:25 p.m.

Director, Freedman and Koski Inc.

4:25 p.m.

Conservative

Phil McColeman Conservative Brantford—Brant, ON

It's my understanding that medical cannabis and recreational cannabis are two different categories. Did the taxation of medical cannabis differ from the taxation of recreational cannabis in Colorado?

4:25 p.m.

Director, Freedman and Koski Inc.

Andrew Freedman

Thank you, sir.

I was part of the Colorado government. In fact, I was the governor's point person during the rollout from 2014 to 2017 of both medical and adult use cannabis. We taxed medical cannabis at a rate of 2.9% sales tax. Adult use had both a 10% excise tax and an additional 10% sales tax, along with the regular 2.9% retail tax. All those taxes on the adult use side have gone up. The medical tax has remained at 2.9%.

4:25 p.m.

Conservative

Phil McColeman Conservative Brantford—Brant, ON

That's a greatly reduced rate. Is that how other medical products are taxed—at 2.9%—or are they taxed at all in Colorado?