There's a lot of interest in some quarters of the world in working with the Africans on the crops that are important to Africa. I know, for instance, there's a big project on cassava and trying to get better yields and better disease and pest resistance. That addresses a very real need. It's the staple crop of some countries in Africa, and there's no way you're going to substitute something for it, realistically.
So yes, there are situations like that, and the risk tolerance will be higher in situations like that. This kind of decision will be taken over and over again in different contexts.