Ultimately what we're looking for is access to the content, and that could be done in a few different ways. I suspect where it gets a little technological, though, is that DRM can often make it so that it's not possible to use some of the screen readers or some of the software that we would normally use to access text in, say, a Microsoft Word document, and that you can't use to read a book from Amazon's Kindle store, for example.
I think what needs to happen is that Amazon has to build in some accessibility. If they want to maintain that DRM, then they can build in a screen reader that will allow you to access it that way. Ultimately it is an issue of accessing the material.