I'm sorry to hear that, Melissa.
I think this problem of cumulative effects is extremely important for us to consider, and it is something that's illustrated in the concept of vulnerable populations, because what we see is these combinations of effects and combinations of exposures, and these differ for different populations. When we're thinking about the myriad of exposures that we have, some of them are not in our control. Some of them are, but for many people, they are not things that are in their control.
When we are looking at assessments of substances, whether they're toxic and whether we need to be reassessing or substituting, this concept of cumulative is really important, because these combinations have an impact on human health.