No, I don't think so.
With respect to GDPR, there are some changes. For example, they assert that an IP address and a time is personal information. That would prevent you from using things like pixel to show an ad to somebody who has previously been on your website, without knowing who they are. That would certainly change, but that would be implemented by Google or Facebook, or whatever advertising platform.
With respect to the work we do with clients, the services we provide would generally be the same, other than whatever specific regulations might go around it.