It is possible because it's being done elsewhere, in other provinces and territories, where the two forms have been combined. The only caveat I'd like to bring to your attention is that, given how complex the two tax regimes are and the differences between them, it's going to be a long questionnaire.
When you look at tax filing software, a great deal of effort is made to assist people who file electronically. The software tries to fill out the various input fields to make filing the tax return as simple as possible.
We continue to work with Revenu Québec to improve the client experience, but the differences between the two systems still stand. Forms can be combined into a single form, but given the differences, the form will be complicated.