I'm happy to.
Absolutely, as Dave mentioned in his opening remarks, insulin is a life-sustaining therapy for people with type 1 diabetes. If they were to not administer insulin, after a very short period of time they would be at risk of having dangerously high blood sugars, potentially leading to avoidable hospitalizations, coma or even death.
Our standard of care is to deliver insulin, as we call it, “intensively”, which means either through multiple injections per day with each of those injections needing to be thought about and calculated, or through an insulin pump, which again is still being delivered on a 24-hour basis, still with multiple calculations and adjustments that need to be made each day. Insulin is absolutely a 24-hour, life-sustaining therapy.
Also note that in type 1 diabetes, there are no other medications approved for treatment. We have one medication, and that is insulin.