Without doing the math, the easy answer is that you take all the pups that are born--that's the simplest thing--but you're not going to see any change in population size for about four to five years. It takes four to five years before they become mature, and it's at that stage that you start to see the impact of your culling program, if that's what you want to do. You either do the pups, take a lot, or you would address your efforts towards reproducing females to have a more immediate impact.
On November 9th, 2006. See this statement in context.