Yes. I'd say that with ISA—I'll just follow up from what Jeff was saying—the classic example for ISA would be what happened in Chile. You're probably quite familiar with the collapse of the industry there as associated with the outbreak of ISA in that region.
In Norway they've had a couple of examples of outbreaks and diseases, some associated with aquaculture and some associated with just transferring fish to another area. I think one of the best examples is probably Gyrodactylus. That was not introduced into Norwegian waters by aquaculture; it was the process of transferring fish associated with hatcheries from the Baltic to the Atlantic.
As a consequence, Norway has since had to deal with about 40 to 50 rivers that have basically been destroyed—with almost no salmon left in them—by this external parasite that is a freshwater parasite that destroys all young salmon. They then go through the process of having living gene banks, which is a very expensive process to maintain the fish. They also then have the process of rotenoning rivers, which sounds quite horrible but basically kills off all sorts of organisms in the river with the hopes of restoring the populations of salmon in subsequent years.
Sometimes it works, but when it's a big river, it often fails. A lot of money has been sunk into this, and it's an ongoing process. Once you have it, it's hard to eliminate it. The idea is to be cautious at the start.