I can start on that one, Member.
When new information becomes available, we assess its significance in terms of what action we might want to take. We have various levels of action. They stem from providing an information update on a product, perhaps a change in the label in terms of the use, to issuing an advisory of some kind--warnings or removal of the product. We have that entire continuum of actions available to us, depending on the nature of the information. In this case we have the large-scale follow-up study. That's going to be a very important source of information, one way or the other. That's basically how we would assess things from the information that comes to us.
Sorry, once again I forgot the second part of your question.