Could I please add something on frequency?
The question of frequency is an interesting one. Increasingly, we have access to data comparing the frequency of adverse reactions experienced by patients taking a given drug compared to those experienced by patients taking a placebo, a pill with no therapeutic benefit. The data shows that the instance of adverse reactions is very high amongst those taking the placebo. What should we do when faced with the fact that, often, patients who have not even taken a drug experience adverse reactions? It is a question of culture and of the individual patient. It is important to be cautious here. I understand that a 10% shortage in pharmacists is worrying, or even catastrophic, but we have to maintain perspective.