We have a memorandum of understanding with Canada. It allows us and Health Canada to share information. We've found that very useful.
In the end, I think it's important to understand that each society may have its own different idea about risk and benefit. This may vary from one country to another, although I think Canada and the United States are probably pretty similar in these ideas.
In terms of risk management and other things, these involve many aspects of the health care system. They depend on the health care system structure as well as individual scientific determinations about risk and benefit. There are some harmonization procedures we have with Europe and Japan, such as the International Conference on Harmonisation, but those are in terms of clinical trial data, which is largely about format, number of patients, and things like that.
I don't know if that answers your question.