Maybe I can add some information about its distribution.
That newsletter is distributed to 67,000 physicians in conjunction with the Canadian Medical Association Journal. It's also printed and distributed to an additional 26,000 health care professionals, mostly pharmacists. It's also sent to all the professional associations of pharmacists and physicians in Canada so that they can send it back to their members.
There's also the MedEffect e-Notice, which is basically a site where people can register or be subscribers and then be informed of all the emerging safety issues in Canada, which also includes publication of the CARN.