Thank you, Madam Chair.
I wanted to probe the topic of off-label use in Canada. Could you share with us some information on how frequent it is and whether Health Canada has concerns about it?
We've heard terms like “drug cocktails” in relation to treatments for cancer and AIDS and other new or complex diseases. We've also read information that off-label use is more frequent with rare diseases and also that there's a greater frequency of off-label use when it comes to pediatrics. Could Health Canada share with us a little more description of off-label use and any concerns you may have regarding it?