No. I think there has been some misinterpretation of what the 48-hour rule should be. We always talk about evidence-based medicine, but what we don't recognize is that if the group you studied isn't the group you're treating, there is no evidence, basically.
What we found, and what we know, is that if you have mild disease and you get antiviral therapy within 48 hours of the onset of symptoms, you have about one day less of symptoms before you get better.