Thank you, Mr. Chair and members of the committee.
Good afternoon, and thank you for inviting me.
My name is Gail Hansen. I'm a public health veterinarian and I'm a senior officer with The Pew Charitable Trusts.
I have worked on antimicrobial resistance issues from a lot of different perspectives for over 30 years. I was a state public health veterinarian and epidemiologist with the Kansas Department of Health and Environment, and with a local health department. Before that, I was in private veterinary practice. And before that--actually before I got into veterinary school--I actually worked for the U.S. Food and Drug Administration for a short time when they were first looking at eliminating antibiotics from animal feeds as growth promotants.
The Pew human health and industrial farming section partners with public health leaders, with other veterinarians, with agricultural interests, and with consumer groups to preserve the effectiveness of antibiotics by phasing out the overuse of the drugs in food animal production.
Antibiotic resistance from feeding low levels of antibiotics to animals is real and is here, as you've heard. Antibiotics are legally available and they're readily available over the counter and are fed to healthy animals. These are the same drugs that are used in human medicine to fight disease. The antibiotic use in food animals in the United States and Canada is very similar, as is the lack of monitoring the use of other drugs and the reporting of the drugs.
It's also very similar that we are seeing an upward trend in antibiotic resistance in bacteria both in animals and in people, and we are seeing that all over the world. And there is an upward trend in the number of bacteria that are becoming resistant to the antibiotics we have on hand.
The CBC report from last month that found bacteria in about three-quarters of the tested chickens, and all the bacteria being resistant to at least one antibiotic and several of them being resistant to multiple antibiotics was not a surprise to me. In the United States, certainly in 2008, nearly all of the chicken that was tested was contaminated with at least one bacteria. And if one of the bacteria is a salmonella, which we find in about half of our chickens, 38% of those salmonellae are resistant to three or more antibiotics.
So it's not really an overstatement to say that antibiotics are overused in industrial farming to the detriment of human health. Animals are fed low levels of antibiotics for growth promotion and in the absence of disease. This is to compensate for some of the overcrowded and sometimes unsanitary conditions and is used as a fix for good practices. And when bacteria come in contact with low levels of antibiotics, it makes it easier for them to become resistant to antibiotics, the “what doesn't kill you makes you stronger” kind of thing. That resistance gets transferred to people. Ultimately, then, the antibiotics we've used to treat disease don't work for animals or for people.
The CIPARS, the Canadian Integrated Program for Antimicrobial Resistance Surveillance, published in 2010, in a peer-reviewed journal, that they found a rise in ceftiofur resistance in a common salmonella in both chickens and people. Ceftiofur is an antibiotic that's routinely injected into chicken eggs just before they're hatched. That drug, ceftiofur, is nearly identical to ceftriaxone, a drug used to treat children and pregnant women.
In Quebec the hatcheries voluntarily stopped that practice, and when they stopped injecting the ceftiofur they saw a great drop in the resistance of salmonella to ceftiofur, both in chickens and in humans. When they lifted that ban a little bit, again they started to see a rise in the antibiotic resistance in people and in chickens.
The WHO has looked at fluoroquinolones, which is another antibiotic. You may know it as Cipro. When it was first licensed for human therapy, there was no immediate rise in salmonella resistance seen. But then when the Cipro, or fluoroquinolones, were licensed for use in food animals, the rates of fluoroquinolone-resistant salmonella went up both in animals and in humans.
The good news is that we do have effective alternatives to using a low level of antibiotics for farmers and ranchers. The EU has banned the use of antibiotics as growth promoters in meat and poultry since 2006. And the ban on the antibiotics as growth promoters was followed in subsequent years by substantial decreases in food-borne illness in Europe.
It would seem to me that Canadians deserve the same, and you can do it if you follow the EU's lead, it would seem.
In Denmark they have industrial farms that are very able to efficiently raise pork and poultry without the use of antibiotics except when the animals are sick. The farmers give antibiotics when they're prescribed by a veterinarian for a specific disease only. They found that if they just banned the use of antibiotics for these non-therapeutic uses, it wasn't enough. They had to really work with their veterinarians and others to find some other effective management strategies.
This is a very opportune time, because the WHO has declared April 7, 2011, as World Health Day. The focus this year is on antimicrobial resistance, in an effort to safeguard antibiotics for future generations.
The U.S. Food and Drug Administration has announced that it will take two significant steps this year to curb the overuse of antibiotics in our food production. First, the FDA is preparing guidance that we're hoping will advise the industry to not use antibiotics for growth promotion and other non-therapeutic purposes, and to not feed antibiotics to healthy animals. Second, the agency is looking at implementing a ban on the off-label use of a drug called ceftiofur in animals. That drug is vital in treating pregnant women, children, and cancer patients. We can't lose the ability of antibiotics to treat us when we're sick, and certainly not because we're feeding them to healthy animals.
Thank you. I'm open for questions.