Impaired driving is certainly a concern in terms of public safety. There's compelling evidence that in Colorado there are a lot of accidents related to marijuana use and hospitalizations related to these crashes have been going up. I just want to leave that for a minute and go in another direction.
I want to go back to Dr. Jutras-Aswad. Well, I go back to Dr. Kalant from University of Toronto who spoke here. He's a professor of pharmacology. He particularly emphasized the fact that those who start young have the greatest impairment, the risk of depression later, risk of motor vehicle accidents.
We had other evidence, in fact, of impairment in cognitive development, from functional MRI, that in fact there's delayed myelination in the frontal areas, where higher executive functions are developing, where reasoning, problem solving, decision-making...areas that can affect adolescents later in life...even maternal smoking has an impact; it's measurable later in life.
In your review of some 120 studies that looked at different aspects of the relationship between cannabis and the adolescent brain.... That is a concern to a lot of us here because it seems they're starting young. They may be choosing their career path unwittingly at a very young age because they're going to impair their ability to do higher executive functions with their brain that would require greater cognitive engagement.
You talked about the association between cannabis and subsequent addiction to heavy drugs and between cannabis and psychosis. I would like you to expand a little bit on that because your time was limited earlier.