I'll start, if you like. There's certainly no shortage of clinical practice guidelines in any of the areas of drug prescribing. In fact, our problem in many ways is not that there's not enough information, but that there's in fact too much information. The difficulty for family physicians often is deciding which guideline to pay attention to and which part of which guideline to pay attention to.
Certainly, guideline-based prescribing is an important part of the care we give, but one of the difficulties is that guidelines are often very dense technical documents that are full of recommendations, many of which are not prioritized and all of which might pertain to a given patient, and many of which may not. We have the task, in applying guideline-based care, of deciding what guidelines to apply to what patients and to recognize that we have many patients who have seven or eight guidelines that apply to them in any given clinical situation, some of which will conflict with each other.
Guideline-based prescribing is only part of the story. We need to have a way of making our way through the forest of guidelines towards patient care decision-making that encompasses what's best for that particular patient sitting in front of you and for their preferences and values.