If I could make one additional comment, it would be that there's a difference between type 1 and type 2 for prevention and screening. You're talking a lot about type 2, but there is some new research going on that suggests we could screen children and look for biomarkers at ages three and five, and determine who's on a trajectory to get this disease. If you know which individuals are predisposed to it, you could then develop intervention strategies for those people.
I just wanted to delineate the difference between a type 1 and a type 2 strategy.