Thank you, Mr. Chair.
Let's start with Janssen. I have a rare disease in my family called Alport syndrome. It's a very personal thing for me. I guess my family would not be the ones you would think of. I thought genetic diseases were about people who were interrelated having kids. My wife is from Singapore and I'm Polish, so there's absolutely no way our ancestors are connected in any way.
On rare diseases, drug access is the biggest issue that I see. Too often I see people talk about the sticker shock—that was mentioned in the presentation—of seeing the final price for a particular rare disorder. The comparison I make is that I see sticker shock whenever I see a Lexus or BMW, but what I don't see is the bargaining agreement, the plant, the investments in dollars, the researchers, in the case of drugs. All of that cost is baked into it. Part of that is also clinical trials.
You're a company that does clinical trials. How long is it taking, and what are the costs baked into it? That portion of it has a big impact on the final price tag, and then there are the negotiations that you do with the different provinces and pCPA and the private companies as well.
Can you talk about that cost structure?