With all due respect to the same caveat my friend gave, we're not really in a position to comment about how this may change. It involves expertise and understanding of the disease and of the arising science in a much more comprehensive manner than I could profess to understand and, therefore, modify a program based upon it.
Again, our role is limited to executing the program as designed and delivered to us as a third party administrator, not to sit and ask what about this and what about that, unless doing so is contemplated in the engagement from the outset.