When we do expert opinion recommendations, we state it. It happens that we have to do such a thing; that's why we're an expert committee. It's the same thing when I treat a patient; I don't always have all the data, and I don't always have all the facts in the science to be able to treat that patient, because it's something unique. You have to take the data and generalize it to your patient's clinical scenario.
It's the same thing here. It's something that hasn't been seen before. So yes, it is an expert opinion, and we say so.