Thanks for that question.
I think I'll put it this way, Dr. Ellis. There are published case reports in the literature of people dying of an overdose from the accidental administration of three milligrams of hydromorphone in a hospital setting. There are multiple cases of that, and that's why it's a high-risk medication and why we go to so much effort to label things as morphine versus hydromorphone. Hydromorphone is extremely potent and could kill a person with no trouble if they don't have opioid tolerance.
Fentanyl is 50 times more potent that morphine, and that number of grams of fentanyl is certainly an amount that could easily kill one or more people.