There's been a growing body of literature over a very long period of time that has linked EBV to MS. I think that the push in the field, the belief that this is really important and the strongest risk factor that we might be aware of today, was at a military database. They had biological samples and could look back 20 years, and it was the single viral indicator for everybody who ended up getting MS. I think that has really pushed forward the EBV story.
There are three EBV vaccines currently under development, one of which is an mRNA vaccine like a COVID-type vaccine. Importantly, there are other antiviral medications, many of which are available to us today, that might play as important a role as perhaps a vaccine will.
I don't believe it's realistic to think that, if a vaccine became available tomorrow, we would vaccinate the whole population. I don't think that's the most successful prevention strategy that we'll have available to us, but if you know that at-risk population that Dr. Marrie just talked about, then maybe you can deploy a vaccine or an antiviral, particularly early in the disease core. I don't think there will be one strategy at the end of the day; I think there will be multiple strategies.