Thank you for your question.
I think the most important thing is the global surveillance system, as you've said. Because surveillance has improved and genomics have improved, we are able to monitor these variants.
Yes, it's quite possible for these variants to come from countries that have lower vaccination rates, but I think this virus is evolving. As we exert pressure on this virus from an immunological perspective, whether it's from the vaccine or from prior infection, the virus will continuously adapt.
It may come from a country with a higher bulk of viruses and transmission—that is true—but we have to remember that the virus can come maybe all of a sudden from a place you don't expect, including maybe from an immunocompromised host.