Health Canada, of course, has a well-established process in evaluating both the safety and the immunogenicity of the vaccines. After any vaccine is launched, we will have post-implementation studies, especially on safety, but also on effectiveness.
As you've indicated, millions and millions of doses of these vaccines have been utilized globally. Just because we are adjusting one of the strains, that doesn't mean that any of the other processes would change. The manufacturing process and the way the vaccine is made have been assessed as usual.
One of the best analogies I could make is that it's a bit like changing influenza strains and updating them every year. A similar kind of concept is being used by the regulator. We know a lot about these mRNA vaccines and their safety. We're just swapping out and updating the strain itself.