Thank you, Mr. Chair.
Mr. Chair, committee members and witnesses, thank you for this opportunity to appear as a full professor from the Université de Montréal and director of the host-virus interaction laboratory at the CRCHUM, Montreal.
I am the co‑founder of Quebec's COVID pandemic network, the RQCP, which I co‑managed until 2022. I am also a member of the Coronavirus Variants Rapid Response Network, or CoVaRR‑Net, which is funded by the Canadian Institutes of Health Research.
I have no conflicts of interest to declare today.
During the initial outbreak of COVID-19, it was evident that children were much less affected by severe acute respiratory symptoms than adults, and particularly the elderly. These observations guided initial public health policies. Children were included in population health measures to limit the general impact of COVID-19 on vulnerable people and to protect the capacity of our health system, rather than to specifically protect their health.
Across Canada, different measures have been taken to limit the transmission of the virus, including at different times the closure of schools, the use of remote education, mask mandates, vaccination or the use of air purifiers. It is reasonable to note that these measures have certainly had negative impacts as described by social science experts.
The optimistic assessment at the start of the pandemic regarding the impact of COVID-19 on children has led to many questions about the relevance of the sanitary measures imposed on children. However, considering that knowledge of COVID-19 has only been made as the pandemic has progressed, several scientists, including me, have supported the application of the precautionary principle in the management of COVID-19 for children.
What is the state of knowledge after three years of the pandemic?
First, the airborne transmission of SARS-CoV-2 is now recognized by the World Health Organization and other public health bodies, and has achieved consensus among the scientific community. It is now clearly established that COVID-19 is transmitted in schools and spreads from schools to homes. Not all children are equal when it comes to complications from COVID-19, and some of the children are also living with relatives who have vulnerabilities to complications related to COVID-19.
The first serious complication observed in children was the multisystem inflammatory syndrome, which has had an incidence of up to six to 10% depending on the age group according to certain studies before 2022. The omicron variant, however, led to a significant increase in transmission among children, accompanied by a major increase in hospitalizations.
It is now clearly established also that COVID-19 is not a disease of the respiratory system only. The acute phase presentation was only the tip of the iceberg. There is now ample evidence of the short- and long-term effects of infection and reinfections. Several studies have now described neurological, cardiovascular and other multisystem impacts of COVID-19 in adults and children independent of the initial presentation of their disease. We can easily imagine that long-term illness will have a major impact on the social well-being and learning ability of children.
The immunity established by vaccines and past infections does not confer complete and infinite protection against reinfections. Immunity to SARS-CoV-2 infection remains relatively short, leaving the children vulnerable to reinfections leading to lost learning days.
We have made a lot of progress in the face of COVID-19, it must be recognized, however, we must draw lessons from our current knowledge. The risk of SARS-CoV-2 infections on children cannot be ignored. Therefore, what is the avenue that we should take in this context to ensure, in the least restrictive way possible, the health but also the learning of children?
Were we right to use methods of limiting transmission in schools given what we know today? My answer is most definitely yes. The precautionary principle and the measures put in place have made it possible to limit infections that have potential for long-term effects. Relying on hybrid immunity established by vaccination and repetitive infections involves the risk of developing long-term complications, the post-vaccination rate of which remains to be determined with accuracy. This risk is not acceptable.
There is an urgent need to consider airborne transmission of SARS-CoV-2 in infection prevention and control. Ignoring it is no longer an option for the long-term management of COVID-19. One of the key measures that must become a priority in our schools, but also in busy public and private environments, is the improvement of indoor air quality through sustainable measures that do not depend on individual human behaviour. Some countries have already committed to implementing such measures, and we must follow in their footsteps to enable a passive reduction of airborne transmission, and thus reduce the need for the use of restrictive personal protective measures. Good indoor air quality has the advantage of protecting against COVID-19 infection, independent of circulating variants, but it also protects against a wide range of other respiratory infections.
Improving indoor air quality is a new frontier in public health, requiring commitment from our leaders at both local and political levels. Just as access to clean water has eliminated the transmission of certain infections in the past, improving air quality will reduce the impact of airborne viral infections.
Thank you.