I would say that it all depends on the type of structure used.
As an example, one of the groups that we work with is the angel investment community. By angel investors, I'm referring to individuals who would finance or take the highest risk associated with a particular investment. In some cases, I've seen angel investors who are completely passive with regard to an investment. They just put their capital in, and let the entrepreneur be the entrepreneur.
In fact, with some models, there's more autonomy for that type of investor than you would ever get with a government funded granting program or a charitable program. It depends on what you mean by autonomy, but In a lot of ways, the level of involvement that's needed in order to satisfy the conditions of a grant can often create barriers to autonomy for a lot of groups.
So what about autonomy in terms of the ability of entrepreneurs to be creative with their investment? If an entrepreneur were able to negotiate a particular set of terms in order to ensure autonomy with the investor, he or she would find that a lot of private sector actors who place capital with the entrepreneur at the direct level rely on that entrepreneur to be successful. They are trying to create the conditions for autonomy and independence. Often, they place less restriction on how that capital can be used and what kind of outcomes they're looking to achieve. In other cases, organizations that look for grant capital or philanthropic capital have to align with the requirements of the funder. In many cases, they have to change the way they run their business, or they have to compromise their vision in order to satisfy the terms of their granting partners.
It's a complex question. It depends on the source of capital, how it's used, and who's actually participating.