Thank you very much, Dr. DeGagné and Dr. McCormick, for your remarks. We're very grateful for those.
We'll move right into a round of seven-minute questions. Members will have seven minutes for both the question and the response and, as always, I'll try to urge members to get to the point of their question as soon as possible, so we can hear more from you.
The first question is from Mike Bossio, please.