This is a question we've been thinking a lot about, and in fact we're doing some studies on it now. We're meeting with vice-presidents of research at universities, we're talking with partners, and so on. My sense is that we're not going to end up with a simple formula, a cookie cutter that we can use.
I think the approach that's been taken--and I think it is working well--is to have a multiplicity of tools, a multiplicity of instruments, and it's going to be an ongoing question of increasing or keeping stable, and so on, across a whole diversity and multiplicity of instruments such as you've described.