Well, I can't talk about numbers globally. There are estimates that put the software industry's losses to counterfeiting and piracy each year at over $60 billion. For the companies that make software, develop it, manufacture it, and distribute it, if they're not getting paid for it, that's money they can't put back into development, and money they can't put back into employing people, and money they can't put forward towards developing new products. So it definitely has a major impact on software companies.
On June 7th, 2012. See this statement in context.