Definitely that has been the case since the inception of the current regime in Iran. Indeed, when they executed many of the political activists in Iran in the 1980s, they buried them in American flags, basically portraying them as agents of U.S. imperialism and things like that.
Meanwhile, everyone inside the country knew well that this had nothing to do with foreign interference. I guess this session does not allow me, and we don't have much time to go into the general politics of this, but purely from an Iranian internal perspective, this is only an alibi that Khomeini, the founder of the Islamic Republic, used to basically rally people in the region behind him. We are anti-American, so you have to support us in our fight against imperialism.
It has nothing to do, in reality, with the pluralistic views of the Iranian people.