The challenge with TRIPS flexibilities is not just in the letter of the law or what is technically written into it. It's in the actual applicability of those flexibilities. As Mr. Lipkus mentioned, many countries are also bound by bilateral trade deals with the U.S. or Europe or the U.K. or Canada or others. Then there are extra trade deal pressures that are often brought to bear against countries that try to exercise TRIPS flexibilities. Even though these are legal under the TRIPS framework, that does not mean there is no consequence for trying to exercise them.
It is my opinion that if these flexibilities could be exercised without retaliation or threat thereof, or without constraint within other bilateral trade deals, they would be sufficient. However, as it is, they are problematic.