It's certainly an area of interest, as you well note, especially when it comes to dealing with our negotiating partner to the south.
Has it prevented agreements? Clearly, it hasn't. We had the FTA with the United States first; then we had NAFTA, and now we have the CUSMA, so no, it has not prevented agreement.
Generally speaking, when we're talking about.... Trading goods tends to take more of a focus than trading in services, such as cultural issues.