It varies by country. The U.S. is a good example. It depends on the sector. The American federation works a little differently from ours, so the jurisdiction can shift depending on the setting. For sanitizers that are used in a manufacturing facility, yes, there are state-level requirements that complicate the ability to do business. On the other hand, in the drug world and the health product world, generally speaking, the U.S. very much operates at a national level.
Those are really tough problems to solve. I wish I could offer you....