Very briefly, to add to what Nigel has said, there is an urgency with respect to this whole issue, and it affects a lot of the folks in this room. It's the baby boom generation.
The statistical onset of ALS is in the 55 years to 70 years age range. While it's being diagnosed in younger people, statistically the large size is in that age range. We all know the baby boom bubble is moving along, and consequently the statistical likelihood of more diagnoses of ALS is imminent.