Certainly. There are a few different ways to think about this. One is in terms of the effect it might have on swaying an American election, both in the sense of whether there might be Russian interference and also broadly in terms of the direction in which the American people will decide to vote. Certainly some administrations and some policy positions will be easier for Canada to deal with than others will.
The other thing to be concerned about is the fact that individuals inspired by these kinds of narratives to take political action, whether it rises to the level of criminal activity or security activity, could be on either side of the border. The media landscapes in Canada and the United States are very closely integrated. This is not to say that there aren't separate causes in both countries, but we do see groups being inspired by each other across the border, and also groups that simply exist transnationally that might take action.
Canada's maintaining and diversifying our relations with the United States can help to make sure that our interests continue to be heard, even if we have a change in government.