Yes. I've been trying to study olanzapine for youth with anorexia nervosa since 2001. It's one of my major failures because it has taken tonnes of time and tonnes of money, and I just can't get enough subjects to agree to be in it. That's partly because if the parent says yes, the teenager says no, and if the parent says no, the teenager says yes. It's hard to get consent from everybody to be in a research study about a medication when you're not sure about the effects on your child. They just worry about their child being a guinea pig, so it's been very hard to recruit into it.
On February 24th, 2014. See this statement in context.