Yes. I think that Professor Quinn is nudging up to what you have to do. It's really the assessment of whether the drug has caused a reaction. In this case, we know the natural history that an acute reaction is associated with a probability of a longer term reaction. So you need to know, was the drug given? What dose was given? Was it taken? How long was it taken? What are the individual's risk factors? What is the uniqueness of their symptomatology? What's their past history of anxiety, depression and so forth? And if you do that systematically, you can determine whether mefloquine was involved in the evolution of the symptomatology. It's nice to have a diagnostic category, but with neuropsychiatric kinds of issues, you're going to have a mixture of signs and symptoms.
On May 13th, 2019. See this statement in context.