That's a safer alternative because it doesn't have the profile of neuropsychiatric events that have been seen with mefloquine from the very beginning. Right from the 1980s it was known that neuropsychiatric events were associated with this drug. In 1989, the World Health Organization put out a technical document that said that people operating heavy machinery should not use this drug. In 1991, they reiterated their concern about the neuropsychiatric events, saying there really needed to be more research about these events—what causes them, how they can be mitigated and how they can be prevented completely.
From the outset, mefloquine has been known to be unsafe in terms of its neuropsychiatric profile. That's why I said it's uniquely dangerous in soldiers because soldiers have to be at peak performance psychologically to do their jobs.