If I may briefly add to that, another population that has taken the medication is journalists, because they have often gone and followed the military. We don't have a good study there, but many journalists I talked to said they took it the first time but would never take it again. They didn't have to take it, or they went to a travel medicine clinic that told them to stay away from it, or they could afford the more expensive Malarone.
One challenge is that if you're at a small pharmacy, for example at Fort Polk, and you have 1,200 soldiers who are deploying, and you have a choice between Malarone, which costs $3 a pill, and mefloquine, which costs 30ยข or so for a week, and you're giving six months' supply to those 1,200 soldiers, choosing Malarone would add a significant cost to your budget.