Yes. In the past, one reason we used mefloquine was because of cost issues, and also it was believed that people would be more compliant with a once-weekly dosage. However, the cost is little compared to the cost of lives or things like massacres. In terms of compliance, what we find is that people are less compliant with mefloquine because they've heard about it and the scary side effects, so they don't take it and are more likely to develop malaria.
On October 25th, 2016. See this statement in context.