I'm not a primary care physician prescribing this, but in my day, I took malaria, when I was in Rwanda, so I had a few nightmares, had a few things. For me, if I were to deploy again to Africa, I'd probably ask for mefloquine again, because I prefer the devil you know. Yes, I had a few side effects but the other medications.... Taking doxycycline for three months, six months, every day, doesn't appeal to me. There were the side effects.
So you're always balancing the risk to the individual of the medication versus the disease. Again, having been in Africa and having seen cerebral malaria, seeing people die from that, it's not a pretty sight. You want to stop malaria and then you want to give them the safest option for them to prevent the malaria, and then all of these agents are designed to kill an organism within your body, but not kill you. It's just like chemotherapy; it's this kind of idea.
Mefloquine is one of the options. Malarone is one of the options.