It's my understanding that if you want to market your cosmetic, you have to notify the government that you're doing so. There are different types of cosmetics. If it's a cosmetic that is not making a therapeutic claim, then it would have to have a notification. If it is making a therapeutic claim, it has a pre-market assessment. Then there's the natural health products area, where there's a list of substances and if you fall within that category you have a natural health number review process as well.
I'm not familiar enough with it to know what the distinctions are, but most of the substances are on the in-commerce list that they would use if they're not new. So if they're existing, they're on the in-commerce list or they're on the domestic substances list.