Indeed, one of the problems we are facing is multiple drug resistance. Malaria drugs are delivered in combination in order to prevent resistance from developing. What the world saw the last time it was using single-dose therapies was that resistance developed very quickly.
We develop medicines in combination and they're delivered in combination. Unfortunately, because malaria is so common, because the parasite is so virulent, we're developing resistance now to several different medicines simultaneously.
The result of this is that, as Hervé said, the global community is working very hard on containment, but we really must have an entire portfolio of medicines to back up each one of the ones currently being used in order to stay ahead of resistance.
Resistance really could be catastrophic. It's easy to come and pound the table and tell you that the sky is falling, but what has happened is that as we are fighting malaria very well, fewer and fewer people are developing natural resistance, so it becomes critically important that we genuinely have a full pipeline of medicines that will be able to support us.