I would just like to add a very brief comment to what Dr. Kahan has said. The difference between smoking and oral use of cannabis or pure cannabinoids is that when you inhale the cannabis containing the THC it is absorbed into the blood and reaches the brain more rapidly than when it's taken by mouth. So it delivers an effect more rapidly, and if you were using the drug to relieve nausea and vomiting, for example after drug treatment for cancer or for other chronic diseases, the relief may be produced more rapidly. The blood level and the brain levels rise very rapidly when you smoke, but fall very rapidly as the drug is redistributed throughout the body. When it's taken by mouth the absorption is slower but more even and longer sustained and therefore the effect is not as intense but it is longer lasting.
As Dr. Kahan has said, for the relief of pain for example, it is a greater advantage than a sudden rapid onset, whereas for relief of vomiting, something can be said in favour of administering it by the more rapid route, but again its duration is less.