We are talking about a baby dose of Aspirin, 81 milligrams. It wouldn't be our recommendation that everyone who is at low risk of acquiring HIV take aspirin. This would be a focused intervention for people who are at extremely high riskāfor example, sex workers or others who face extreme risk. We would advise them to take a number of approaches, including using condoms, reducing the number of partners and using antiretroviral drugs, as well as taking aspirin.
Some people don't have antiretroviral drugs available, and others aren't in a position to negotiate the use of a condom, so maybe an aspirin would be something they could use that would be available and not stigmatizing. Each person would have to decide which was the best approach for them. I would not recommend that anyone use aspirin as their sole HIV prevention. It would reduce risk, but it wouldn't eliminate it.