Thank you for your question.
I agree entirely; more research is needed. In our experiments, we have always worked with frequencies, but that is just one small part of the parameters that influence sound quality. We have little knowledge about many parameters.
If we were able to know more, we could then try to control the part of the software and hardware used by everyone affected by this communication process in order to have the best equipment on site. However, people connect via their mobile devices or from their cars, where we cannot control anything.
In my opinion, for the moment, the only possible solution is to reduce the time that the interpreters are exposed to these parameters.