I could respond very quickly to that.
The main change, as I understand it, and I would encourage you to ask this question of PCO when they're here, because they were responsible for changing elements of the protocol.... From a SITE perspective, our mandates remain the same. We adhere to the mandates and the authorities we have. From a composition perspective, that didn't change. From a protocol perspective, I understand there were changes that I would encourage PCO to speak to tomorrow.