Yes, there are multiple differences on different levels. One is how women have been treated by society because of the state's repression. It's really different from how men are treated.
I was prosecuted in Egypt as part of the foreign funding case, and I got one of the charges against me dropped. None of the others, men or other women, got that.
I support women having “irresponsible liberty”. There is something about morals such that they affect women human rights defenders more than men.
Also, there is an effect on their personal life that is different for women than it is for men, because within the system, people can respect men taking outrageous actions more than women.